About Diabetic Peripheral Neuropathy

Diabetic peripheral neuropathy is a painful nerve pain condition that affects more than 20 million Americans.  Here at Desert Pain specialists we keep current with any new treatments that may be beneficial to our patients.  For many years, there were not many treatment options for people with diabetic peripheral neuropathy.  However, there are a couple recent treatment options that have emerged with FDA approval.  One of those options is spinal cord stimulation, thanks to a journal article that appeared in JAMA Neurology in April 2021 proving that high frequency spinal cord stimulation was very effective at treating diabetic peripheral neuropathy pain.  Please contact your Desert Pain Specialists physician for more information about this procedure.  Also, ask us about our free education class on peripheral neuropathy.

What Causes Diabetic Peripheral Neuropathy?

Diabetic peripheral neuropathy (DPN) is a common complication of diabetes caused by prolonged high blood sugar levels damaging the peripheral nerves, primarily in the hands, feet, legs, and arms. Chronic hyperglycemia leads to oxidative stress, the formation of harmful advanced glycation end products (AGEs), and inflammation, all of which contribute to nerve damage. Additionally, impaired blood flow due to microvascular complications and abnormal lipid metabolism further exacerbate the condition. Genetic predisposition and lifestyle factors like smoking, obesity, and inactivity can increase the risk of DPN.

Symptoms include numbness, tingling, burning sensations, sharp pain, and muscle weakness, often beginning in the extremities. Prevention and management focus on maintaining tight blood sugar control, adopting a healthy lifestyle, and addressing risk factors. Medications such as antidepressants or anticonvulsants can help manage pain, while regular foot care can prevent complications. Early diagnosis and intervention are crucial to slowing progression and improving quality of life.

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